Sildenafil (Viagra), hemodynamics and the lung

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Measurement of choroidal perfusion and thickness following systemic sildenafil (Viagra(®) ).

PURPOSE To demonstrate anatomic and physiologic changes in the human choroid following systemic sildenafil citrate (Viagra®) using enhanced depth imaging spectral domain-optical coherence tomography (EDI-OCT) and swept-scan high-frequency digital ultrasound. METHODS Seven healthy male subjects (mean age 32.7 years) were evaluated at baseline and 2 hr after ingesting 50 mg of sildenafil. Swept...

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Sildenafil (Viagra) Induces Neurogenesis and Promotes Functional Recovery After Stroke

Ruilan Zhang, Ying Wang, Li Zhang, Zhenggang Zhang, Wayne Tsang, Mei Lu, Lijie Zhang in Rats Sildenafil (Viagra) Induces Neurogenesis and Promotes Functional Recovery After Stroke Print ISSN: 0039-2499. Online ISSN: 1524-4628 Copyright © 2002 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231 Stroke doi:...

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Effect of sildenafil (Viagra) on cerebral blood vessels.

Sildenafil is a selective inhibitor of phosphodiesterase type 5 and is used for the treatment of male erectile dysfunction. It causes relaxation of vascular smooth muscle via a cyclic guanosine monophosphate (cGMP) second messenger that results in a vasodilatory effect in the corpus cavernosum. A dilatory effect on peripheral blood vessels has also been identified and vascular side effects prim...

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Sildenafil modulates hemodynamics and pulmonary gas exchange.

The effects of sildenafil (Viagra) on hemodynamics and pulmonary gas exchange remain uncertain. The aim of this study was to investigate what effect sildenafil had on gas exchange. A total of 24 anesthetized pigs were randomly assigned into four groups of six animals each: Group Low received 25 mg of sildenafil, which is equivalent to half the recommended dose for humans; group Normal received ...

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Sildenafil improves exercise hemodynamics in Fontan patients.

BACKGROUND Patients with Fontan circulation have reduced exercise capacity. The absence of a presystemic pump may limit flow through the pulmonary circulation, restricting ventricular filling and cardiac output. We evaluated exercise hemodynamics and the effect of sildenafil on exercise hemodynamics in Fontan patients. METHODS AND RESULTS Ten Fontan patients (6 men, 20±4 years) underwent card...

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ژورنال

عنوان ژورنال: Respiratory Research

سال: 2001

ISSN: 1465-993X

DOI: 10.1186/rr-2001-68510